Awọn ọja
M-chlorodiphenylamine
Awọn alaye
Ilana molikula: C12H10ClN
iwuwo molikula: 203.67
EINECS No.: 202-922-0
Awọn ẹka ti o jọmọ: Kemistri Organic; Aromatics
Mol faili: 101-17-7.mol
Yiyọ ojuami: 112 ° C (Solv: kẹmika (67-56-1))
Ojutu farabale: 340°C
iwuwo: 1,21g/cm3
Atọka itọka: 1.6513 (iṣiro)
Awọn ipo ipamọ: 2-8°C
Solubility: Chloroform (Diẹ), MethChemicalbookanol (Diẹ)
Olusọdipúpọ acidity: (pKa) -0.20 ± 0.30 (Asọtẹlẹ)
Fọọmu: Epo
Awọ: Biba Yellow si Yellow
CAS aaye data: 101-17-7 (CASDataBaseReference)
Iṣẹ ṣiṣe ti ara: 3-Chlorodiphenylamine jẹ olutọju ọkan ọkan ti o ga julọ Ca2+ sensitizer (Ca2+ sensitizer).3-Chlorodiphenylamine da lori eto diphenylamine ati pe o le sopọ mọ agbegbe N-terminal ti troponin C (cTnC) ọkan (Kd=6µM).3-Chlorodiphenylamine, nitori iwọn kekere molikula rẹ, le ṣe iranṣẹ bi ibẹrẹ ibẹrẹ ti o dara julọ fun idagbasoke awọn agbo ogun ti Ca2 + ti o lagbara sii fun iwadii ikuna ọkan systolic.
Àfojúsùn Kd: 6µM(N-domainofcardiactroponinC(cTnC))Kd:10µM(cNTnC–cSpchimera)
Kemikali Properties: Liquid.Oju omi farabale: 335-336 ℃ (96.3kPa), iwuwo ibatan 1.200, itọka itọka 1.6513.Soluble ni ethanol, benzene, acetic acid ati ether.
Nlo: m-chlorodiphenylamine jẹ agbedemeji Organic ti diphenylamine, eyiti a lo lati ṣe agbejade oogun chlorpromazine.
awọn ọna iṣelọpọ : nipasẹ ifasilẹ ti o-chlorobenzoic acid ati m-chloroaniline, ati lẹhinna decarboxylated pẹlu erupẹ irin.
Ewu ẹka koodu: 20/21/22
Awọn ilana aabo: 28-36/37
